Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy.

• Main Authors: Hong-Ru Chen (Author), Yung-Chun Chuang (Author), Yee-Shin Lin (Author), Hsiao-Sheng Liu (Author), Ching-Chuan Liu (Author), Guey-Chuen Perng (Author), Trai-Ming Yeh (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) is the most common mosquito-borne flavivirus; it can either cause mild dengue fever or the more severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). One of the characteristic features of DHF/DSS is vascular leakage; although DENV nonstructural protein 1 (NS1) ha...