In vivo evaluation of tumor uptake and bio-distribution of 99mTc-labeled 1-thio-β-D-glucose and 5-thio-D-glucose in mice model

• Main Authors: Fabian Muehlberg (Author), Konrad Mohnike (Author), Oliver S. Grosser (Author), Maciej Pech (Author), Juergen Goldschmidt (Author), Karl-Heinz Smalla (Author), Ricarda Seidensticker (Author), Muzaffer Reha Ümütlü (Author), Sinan Deniz (Author), Jens Ricke (Author), Ingo G. Steffen (Author), Osman Öcal (Author), Max Seidensticker (Author)
• Format: Book
• Published: SpringerOpen, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To investigate the capacity of 99mTc-labeled 1-thio-β-D-glucose (1-TG) and 5-thio-D-glucose (5-TG) to act as a marker for glucose consumption in tumor cells in vivo as well as to evaluate the biodistribution of 1-TG and 5-TG. We investigated the biodistribution, including tumor u...