Role of Metabolic Reprogramming in Pulmonary Innate Immunity and Its Impact on Lung Diseases

• Main Authors: Charalambos Michaeloudes (Author), Pankaj K. Bhavsar (Author), Sharon Mumby (Author), Bingling Xu (Author), Christopher Kim Ming Hui (Author), Kian Fan Chung (Author), Ian M. Adcock (Author)
• Format: Book
• Published: Karger Publishers, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung innate immunity is the first line of defence against inhaled allergens, pathogens and environmental pollutants. Cellular metabolism plays a key role in innate immunity. Catabolic pathways, including glycolysis and fatty acid oxidation (FAO), are interconnected with biosynthetic and redox pathwa...