Exosomal miRNA-155-5p from M1-polarized macrophages suppresses angiogenesis by targeting GDF6 to interrupt diabetic wound healing

• Autores principales: Ruohan Lou (Autor), Jiali Chen (Autor), Fei Zhou (Autor), Tian Zhang (Autor), Xiuping Chen (Autor), Chunming Wang (Autor), Bing Guo (Autor), Ligen Lin (Autor)
• Formato: Libro
• Publicado: Elsevier, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Unprogrammed macrophage polarization, especially prolonged activation of proinflammatory macrophages, is associated with delayed wound healing in diabetic objectives. Macrophage-derived exosomes cargo a variety of microRNAs (miRNAs), participating in different stages in wound healing. Here, exosomes...