The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

• Main Authors: Yan Chen (Author), Qingpu Liu (Author), Zengfu Shan (Author), Yingying Zhao (Author), Meng Li (Author), Baiyan Wang (Author), Xiaoke Zheng (Author), Weisheng Feng (Author)
• Format: Book
• Published: BMC, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Catalpol, a natural iridoid glycoside in Rehmannia glutinosa, can alleviate proteinuria associated with diabetic nephropathy (DN), however, whether catalpol has a protective effect against podocyte injury in DN remains unclear. Methods In this study, we used a high glucose (HG)-i...