Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells

• Main Authors: Gaopan Li (Author), Yuhuan Zhong (Author), Wenyi Wang (Author), Xiaokang Jia (Author), Huaichang Zhu (Author), Wenwen Jiang (Author), Yu Song (Author), Wen Xu (Author), Shuisheng Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The potential antitumor effects of sempervirine (SPV), an alkaloid compound derived from the traditional Chinese medicine Gelsemium elegans Benth., on different malignant tumors were described in detail. The impact of SPV on glioma cells and the basic atomic components remain uncertain. This study a...