Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery

• Main Authors: Sarita Garg (Author), Ratan Sadhukhan (Author), Sudip Banerjee (Author), Alena V. Savenka (Author), Alexei G. Basnakian (Author), Victoria McHargue (Author), Junru Wang (Author), Snehalata A. Pawar (Author), Sanchita P. Ghosh (Author), Jerry Ware (Author), Martin Hauer-Jensen (Author), Rupak Pathak (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Natural antioxidant gamma-tocotrienol (GT3), a vitamin E family member, provides intestinal radiation protection. We seek to understand whether this protection is mediated via mucosal epithelial stem cells or sub-mucosal mesenchymal immune cells. Vehicle- or GT3-treated male CD2F1 mice were exposed...