Eudebeiolide B Inhibits Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Regulating RANKL-Induced NF-κB, c-Fos and Calcium Signaling

• Main Authors: Mi-Hwa Kim (Author), Hyung-Jin Lim (Author), Seon Gyeong Bak (Author), Eun-Jae Park (Author), Hyun-Jae Jang (Author), Seung Woong Lee (Author), Soyoung Lee (Author), Kang Min Lee (Author), Sun Hee Cheong (Author), Seung-Jae Lee (Author), Mun-Chual Rho (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Eudebeiolide B is a eudesmane-type sesquiterpenoid compound isolated from <i>Salvia plebeia</i> R. Br., and little is known about its biological activity. In this study, we investigated the effects of eudebeiolide B on osteoblast differentiation, receptor activator nuclear factor-κB liga...