Mg2+-dependent facilitation and inactivation of L-type Ca2+ channels in guinea pig ventricular myocytes

• Main Authors: Meimi Zhao (Author), Rui Feng (Author), Dongxue Shao (Author), Shuyuan Liu (Author), Ming Lei (Author), Hongmei Wang (Author), Xuefei Sun (Author), Feng Guo (Author), Huiyuan Hu (Author), Masaki Kameyama (Author), Liying Hao (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to investigate the intracellular Mg2+ regulation of the L-type Ca2+ channels in guinea pig ventricular myocytes. By adopting the inside-out configuration of the patch clamp technique, single channel currents of the L-type Ca2+ channels were recorded at different intracellular Mg2+ c...