Mechanism of carvedilol induced action potential and calcium alternans

• मुख्य लेखकों: Elizabeth Martinez-Hernandez (लेखक), Giedrius Kanaporis (लेखक), Lothar A. Blatter (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Carvedilol is a nonspecific β-blocker clinically used for the treatment of cardiovascular diseases but has also been shown to have profound effects on excitation-contraction coupling and Ca signaling at the cellular level. We investigate the mechanism by which carvedilol facilitates Ca transient (Ca...