Mechanism of carvedilol induced action potential and calcium alternans

• Principais autores: Elizabeth Martinez-Hernandez (Autor), Giedrius Kanaporis (Autor), Lothar A. Blatter (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Carvedilol is a nonspecific β-blocker clinically used for the treatment of cardiovascular diseases but has also been shown to have profound effects on excitation-contraction coupling and Ca signaling at the cellular level. We investigate the mechanism by which carvedilol facilitates Ca transient (Ca...