Mechanism of carvedilol induced action potential and calcium alternans

• Auteurs principaux: Elizabeth Martinez-Hernandez (Auteur), Giedrius Kanaporis (Auteur), Lothar A. Blatter (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Carvedilol is a nonspecific β-blocker clinically used for the treatment of cardiovascular diseases but has also been shown to have profound effects on excitation-contraction coupling and Ca signaling at the cellular level. We investigate the mechanism by which carvedilol facilitates Ca transient (Ca...