Modeling time‐delayed concentration‐QT effects with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5a1 receptor) antagonist

Abstract The novel oral complement factor 5a receptor 1 antagonist ACT‐1014‐6470 was well tolerated in single‐ and multiple‐ascending dose studies, including 24 h Holter electrocardiogram (ECG) recordings evaluating its cardiodynamics based on data from single doses of 30-200 mg and twice‐daily (b.i...

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Main Authors: Marion Anliker‐Ort (Author), Chih‐hsuan Hsin (Author), Andreas Krause (Author), Marc Pfister (Author), John van denAnker (Author), Jasper Dingemanse (Author), Priska Kaufmann (Author)
Format: Book
Published: Wiley, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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