Inhibiting HMGB1 with Glycyrrhizic Acid Protects Brain Injury after DAI via Its Anti-Inflammatory Effect

• Những tác giả chính: Honggang Pang (Tác giả), Tinqin Huang (Tác giả), Jinning Song (Tác giả), Dandong Li (Tác giả), Yonglin Zhao (Tác giả), Xudong Ma (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2016-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

High-mobility group box 1 (HMGB1), a nuclear protein that has endogenous cytokine-like activity, is involved in several neurological diseases by mediating inflammatory response. In this study, a lateral head rotation device was used to establish a rat diffuse axonal injury (DAI) model. The dynamic e...