Oxysterols Increase Inflammation, Lipid Marker Levels and Reflect Accelerated Endothelial Dysfunction in Experimental Animals

• Main Authors: Tomasz Wielkoszyński (Author), Jolanta Zalejska-Fiolka (Author), Joanna K. Strzelczyk (Author), Aleksander J. Owczarek (Author), Armand Cholewka (Author), Marcin Furmański (Author), Agata Stanek (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Oxidized cholesterol derivatives are thought to exert atherogenic effect thus adversely affecting vascular endothelium. The aim of the study was to assess the effect of 5α,6α-epoxycholesterol on experimentally induced hypercholesterolemia in rabbits, and the levels of homocysteine (HCY),...