Intrathecally Administered D-Cycloserine Produces Nociceptive Behavior Through the Activation of N-Methyl-D-aspartate Receptor Ion-Channel Complex Acting on the Glycine Recognition Site

• Main Authors: Koichi Tan-No (Author), Akihisa Esashi (Author), Osamu Nakagawasai (Author), Fukie Niijima (Author), Seiichi Furuta (Author), Takumi Sato (Author), Susumu Satoh (Author), Hajime Yasuhara (Author), Takeshi Tadano (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intrathecal (i.t.) administration of D-cycloserine (100 and 300 fmol), a partial agonist of the glycine recognition site on the N-methyl-D-aspartate (NMDA) receptor ion-channel complex, produced a behavioral response mainly consisting of biting and/or licking of the hindpaw and the tail along with s...