Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease

• Hlavní autoři: Valentin Bragin (Autor), Arturo Solís Herrera (Autor), Jerzy Leszek (Autor), Ludis Morales (Autor), Mark E. Obrenovich (Autor), Eldar Gasimov (Autor), Hector H. Palacios (Autor), Gjumrakch Aliev (Autor), Dmitry Gokhman (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2010-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Mitochondrial dysfunction may be a principal underlying event in aging, including age-associated brain degeneration. Mitochondria provide energy for basic metabolic processes. Their decay with age impairs cellular metabolism and leads to a decline of cellular function. Alzheimer disease (AD) and cer...