Denosumab treatment for progressive skull base giant cell tumor of bone in a 14 year old female - a case report and literature review

• Main Authors: Samvel Bardakhchyan (Author), Leo Kager (Author), Samvel Danielyan (Author), Armen Avagyan (Author), Nerses Karamyan (Author), Hovhannes Vardevanyan (Author), Sergey Mkhitaryan (Author), Ruzanna Papyan (Author), Davit Zohrabyan (Author), Liana Safaryan (Author), Lilit Sargsyan (Author), Lilit Harutyunyan (Author), Lusine Hakobyan (Author), Samvel Iskanyan (Author), Gevorg Tamamyan (Author)
• Format: Book
• Published: BMC, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Giant cell tumor of bone (GCT) is a rare primary bone tumor, which can metastasize and undergo malignant transformation. The standard treatment of GCT is surgery. In patients with unresectable or metastatic disease, additional therapeutic options are available. These include bloc...