MicroRNA-10a-3p Improves Cartilage Degeneration by Regulating CH25H-CYP7B1-RORα Mediated Cholesterol Metabolism in Knee Osteoarthritis Rats

• Váldodahkkit: Xiaochen Li (Dahkki), Li Zhang (Dahkki), Xiaoqing Shi (Dahkki), Taiyang Liao (Dahkki), Nongshan Zhang (Dahkki), Yifan Gao (Dahkki), Runlin Xing (Dahkki), Peimin Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Osteoarthritis (OA) is a worldwide degenerative joint disease that seriously impaired the quality of life of patients. OA has been established as a disease with metabolic disorder. Cholesterol 25-hydroxylase (CH25H) was proved to play a key role in cartilage cholesterol metabolism. However, the biol...