Targeting Hypoxia Inducible Factors-1α As a Novel Therapy in Fibrosis
Fibrosis, characterized by increased extracellular matrix (ECM) deposition, and widespread vasculopathy, has the prominent trait of chronic hypoxia. Hypoxia inducible factors-1α (HIF-1α), a key transcriptional factor in response to this chronic hypoxia, is involved in fibrotic disease, such as Syste...
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| Format: | Book |
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Frontiers Media S.A.,
2017-05-01T00:00:00Z.
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