Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice

• Main Authors: Cuiqing Zhao (Author), Liming Liu (Author), Qi Liu (Author), Fengyuan Li (Author), Lihua Zhang (Author), Fenxia Zhu (Author), Tuo Shao (Author), Shirish Barve (Author), Yiping Chen (Author), Xiaokun Li (Author), Craig J. McClain (Author), Wenke Feng (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: High fructose feeding changes fibroblast growth factor 21 (FGF21) regulation. Lactobacillus rhamnosus GG (LGG) supplementation reduces fructose-induced non-alcoholic fatty liver disease (NAFLD). The aim of this study was to determine the role of FGF21 and underlying mechanisms in the pro...