Investigating the Combination therapy effect of Trastuzumab and Idarubicin on growth inhibition of HER2-positive breast cancer cells line (SK-BR-3)

• প্রধান লেখক: Moslem Afrakhteh (লেখক), Majid zeinali (লেখক), MohammadAli Ghaffari (লেখক), Aminollah Pourshohod (লেখক), Mostafa Jamalan (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Fasa University of Medical Sciences, 2017-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background & Objectives: Trastuzumab and Idarubicin (4-methyl-daunorubicin) are two anti-neoplasmic agents that are widely used in cancer therapy. Idarubicin is more lipophilic than its parent drugs such as daunorubicin, therefore  it is absorbed more efficiently by the target cells. The main ai...