Optimization of Maduramicin Ammonium-Loaded Nanostructured Lipid Carriers Using Box-Behnken Design for Enhanced Anticoccidial Effect against <i>Eimeria tenella</i> in Broiler Chickens

• Главные авторы: Yan Zhang (Автор), Runan Zuo (Автор), Xinhao Song (Автор), Jiahao Gong (Автор), Junqi Wang (Автор), Mengjuan Lin (Автор), Fengzhu Yang (Автор), Xingxing Cheng (Автор), Xiuge Gao (Автор), Lin Peng (Автор), Hui Ji (Автор), Xia Chen (Автор), Shanxiang Jiang (Автор), Dawei Guo (Автор)
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• Опубликовано: MDPI AG, 2022-06-01T00:00:00Z.
• Предметы: article
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Maduramicin ammonium (MAD) is one of the most frequently used anticoccidial agents in broiler chickens. However, the high toxicity and low solubility of MAD limit its clinical application. In this study, MAD-loaded nanostructured lipid carriers (MAD-NLCs) were prepared to overcome the defects of MAD...