Optimization of Maduramicin Ammonium-Loaded Nanostructured Lipid Carriers Using Box-Behnken Design for Enhanced Anticoccidial Effect against <i>Eimeria tenella</i> in Broiler Chickens

• Main Authors: Yan Zhang (Author), Runan Zuo (Author), Xinhao Song (Author), Jiahao Gong (Author), Junqi Wang (Author), Mengjuan Lin (Author), Fengzhu Yang (Author), Xingxing Cheng (Author), Xiuge Gao (Author), Lin Peng (Author), Hui Ji (Author), Xia Chen (Author), Shanxiang Jiang (Author), Dawei Guo (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Maduramicin ammonium (MAD) is one of the most frequently used anticoccidial agents in broiler chickens. However, the high toxicity and low solubility of MAD limit its clinical application. In this study, MAD-loaded nanostructured lipid carriers (MAD-NLCs) were prepared to overcome the defects of MAD...