Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes

• Main Authors: Wenwei Liang (Author), Gang Liu (Author), Weibo Zhou (Author), Wei Chen (Author), Yaojun Lu (Author), Hao Wu (Author), Yao Qin (Author), Chunhui Zhu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective This study investigates how astaxanthin (AST) counters tert-butyl hydroperoxide (tBHP)-induced cellular damage in C28/I2 chondrocytes, focusing on the circ-HP1BP3/miR-139-5p/SOD1 signaling pathway and its use in sustained-release microspheres for osteoarthritis treatment.Methods We employe...