An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

• 主要な著者: Eleonora Ciarlo (著者), Sara Massone (著者), Ilaria Penna (著者), Mario Nizzari (著者), Arianna Gigoni (著者), Giorgio Dieci (著者), Claudio Russo (著者), Tullio Florio (著者), Ranieri Cancedda (著者), Aldo Pagano (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2013-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

SUMMARY Recent studies indicated that sortilin-related receptor 1 (SORL1) is a risk gene for late-onset Alzheimer's disease (AD), although its role in the aetiology and/or progression of this disorder is not fully understood. Here, we report the finding of a non-coding (nc) RNA (hereafter refer...