Acute and Sub-Chronic Toxicity Study of 1-(2, 5-Dihidroxyphenil)-3- Pyridine-2-Il-Propenone In Adult Female Mice

• Main Authors: Ika Puspitasari (Author), Ratna Asmah Susidarti (Author), Arief Nurrochmad (Author), Pridiyanto Pridiyanto (Author), Devie Amalia Utami (Author), Pipit Febrian (Author), Thoriq Ziyad (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This research aimed to evaluate the toxicity of 1-(2, 5-dihidroxyphenil)-3-pyridine-2-il-propenone (DPP) after 24 hours and 90-day administration in female mice. Acute toxicity test was performed using the OECD 423 method, and DPP was administered once a day at doses of 300, 2000, and 5000 mg/kg bod...