Molecular biomarkers of Alzheimer's disease: progress and prospects

• Main Authors: Tammaryn Lashley (Author), Jonathan M. Schott (Author), Philip Weston (Author), Christina E. Murray (Author), Henny Wellington (Author), Ashvini Keshavan (Author), Sandrine C. Foti (Author), Martha Foiani (Author), Jamie Toombs (Author), Jonathan D. Rohrer (Author), Amanda Heslegrave (Author), Henrik Zetterberg (Author)
• Format: Book
• Published: The Company of Biologists, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The neurodegenerative disorder Alzheimer's disease is characterised by the formation of β-amyloid plaques and neurofibrillary tangles in the brain parenchyma, which cause synapse and neuronal loss. This leads to clinical symptoms, such as progressive memory deficits. Clinically, these pathologi...