Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

• Autori principali: Eric A Benson (Autore), Michael T Eadon (Autore), Zeruesenay eDesta (Autore), Yunlong eLiu (Autore), Hai eLin (Autore), Kimberly S Burgess (Autore), Matthew W Segar (Autore), Andrea eGaedigk (Autore), Todd C Skaar (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2016-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered expression of these transporters due to drug-...