Modeling breast cancer progression to bone: how driver mutation order and metabolism matter

• Päätekijät: Gianluca Ascolani (Tekijä), Pietro Liò (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2019-07-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the occurrence of very few driver mutations promoting oncogenic cell behaviou...