Antioxidant and anti-inflammatory activities of lycopene against 5-fluorouracil-induced cytotoxicity in Caco2 cells

• Main Authors: Norah M. Alhoshani (Author), Mohammed Al-Zharani (Author), Bader Almutairi (Author), Nada H. Aljarba (Author), Norah S. AL-Johani (Author), Nora Alkeraishan (Author), Abdullah A. AlKahtane (Author), Saud Alarifi (Author), Daoud Ali (Author), Saad Alkahtani (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

5-fluorouracil (5FU) is widely used to treat colorectal cancer (CC) and its main mechanisms of anticancer action are through generation of ROS which often result in inflammation. Here, we test the effect of Lycopene against 5FU in Caco2 cell line. Caco2 cells were exposed to 3 µg/ml of 5FU alone or...