Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy

• Main Authors: Marcin Skotnicki (Author), Barbara Jadach (Author), Agnieszka Skotnicka (Author), Bartłomiej Milanowski (Author), Lidia Tajber (Author), Marek Pyda (Author), Jacek Kujawski (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for potential use in the fixed-dose combination therapy. The system was characteriz...