Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics

Abstract Background Poly (ADP)-ribose polymerase (PARP) inhibitors have entered routine clinical practice for the treatment of high-grade serous ovarian cancer (HGSOC), yet the molecular mechanisms underlying treatment response to PARP1 inhibition (PARP1i) are not fully understood. Methods Here, we...

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Main Authors: Alexandra Franz (Author), Fabian Coscia (Author), Ciyue Shen (Author), Lea Charaoui (Author), Matthias Mann (Author), Chris Sander (Author)
Format: Book
Published: BMC, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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