Microtubule stabilization promotes the synthesis of type 2 collagen in nucleus pulposus cell by activating hippo-yap pathway

Intervertebral disc degeneration (IDD) is the cardinal pathological mechanism that underlies low back pain. Mechanical stress of the intervertebral disc may result in a change in nucleus pulposus cells state, matrix degradation, and degeneration of the disc. Microtubules, which are components of the...

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Main Authors: Xin Zhang (Author), Shibin Shu (Author), Zhenhua Feng (Author), Yong Qiu (Author), Hongda Bao (Author), Zezhang Zhu (Author)
Format: Book
Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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