HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• Κύριοι συγγραφείς: María G Alvarez (Συγγραφέας), Miriam Postan (Συγγραφέας), D Brent Weatherly (Συγγραφέας), María C Albareda (Συγγραφέας), John Sidney (Συγγραφέας), Alessandro Sette (Συγγραφέας), Carina Olivera (Συγγραφέας), Alejandro H Armenti (Συγγραφέας), Rick L Tarleton (Συγγραφέας), Susana A Laucella (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...