HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• Päätekijät: María G Alvarez (Tekijä), Miriam Postan (Tekijä), D Brent Weatherly (Tekijä), María C Albareda (Tekijä), John Sidney (Tekijä), Alessandro Sette (Tekijä), Carina Olivera (Tekijä), Alejandro H Armenti (Tekijä), Rick L Tarleton (Tekijä), Susana A Laucella (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...