HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• मुख्य लेखकों: María G Alvarez (लेखक), Miriam Postan (लेखक), D Brent Weatherly (लेखक), María C Albareda (लेखक), John Sidney (लेखक), Alessandro Sette (लेखक), Carina Olivera (लेखक), Alejandro H Armenti (लेखक), Rick L Tarleton (लेखक), Susana A Laucella (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...