HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• Үндсэн зохиолчид: María G Alvarez (Зохиогч), Miriam Postan (Зохиогч), D Brent Weatherly (Зохиогч), María C Albareda (Зохиогч), John Sidney (Зохиогч), Alessandro Sette (Зохиогч), Carina Olivera (Зохиогч), Alejandro H Armenti (Зохиогч), Rick L Tarleton (Зохиогч), Susana A Laucella (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...