HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• Váldodahkkit: María G Alvarez (Dahkki), Miriam Postan (Dahkki), D Brent Weatherly (Dahkki), María C Albareda (Dahkki), John Sidney (Dahkki), Alessandro Sette (Dahkki), Carina Olivera (Dahkki), Alejandro H Armenti (Dahkki), Rick L Tarleton (Dahkki), Susana A Laucella (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...