HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.
BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...
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Public Library of Science (PLoS),
2008-01-01T00:00:00Z.
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