HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• Asıl Yazarlar: María G Alvarez (Yazar), Miriam Postan (Yazar), D Brent Weatherly (Yazar), María C Albareda (Yazar), John Sidney (Yazar), Alessandro Sette (Yazar), Carina Olivera (Yazar), Alejandro H Armenti (Yazar), Rick L Tarleton (Yazar), Susana A Laucella (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...