The Implication of the Polymorphisms of COX-1, UGT1A6, and CYP2C9 among Cardiovascular Disease (CVD) Patients Treated with Aspirin

The Implication of the Polymorphisms of COX-1, UGT1A6, and CYP2C9 among Cardiovascular Disease (CVD) Patients Treated with Aspirin

PURPOSE:  Enzymes potentially responsible for the pharmacokinetic variations of aspirin include cyclooxygenase-1 (COX-1), UDP-glucuronosyltransferase (UGT1A6) and P450 (CYP) (CYP2C9). We therefore aimed to determine the types and frequencies of variants of COX-1 (A-842G), UGT1A6 (UGT1A6*2; A541G and...

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Main Authors: Nur Jalinna Abdul Jalil (Author), Zakaria Bannur (Author), A. Derahman (Author), O. Maskon (Author), Noor Darinah (Author), Hamat Hamidi (Author), Osama Ali Gunasekaran (Author), Mohd Rafizi (Author), Nur Izatul Azreen (Author), Teh Lay Kek (Author), Mohd. Zaki Salleh (Author)
Format: Book
Published: Frontiers Media S.A., 2015-09-01T00:00:00Z.
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