Low-cost oral metronomic chemotherapy versus intravenous cisplatin in patients with recurrent, metastatic, inoperable head and neck carcinoma: an open-label, parallel-group, non-inferiority, randomised, phase 3 trial

Summary: Background: Regimens for palliation in patients with head and neck cancer recommended by the US National Comprehensive Cancer Network (NCCN) have low applicability (less than 1-3%) in low-income and middle-income countries (LMICs) because of their cost. In a previous phase 2 study, patients...

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Main Authors: Vijay Patil, ProfDM (Author), Vanita Noronha, ProfDM (Author), Sachin Babanrao Dhumal, BHMS (Author), Amit Joshi, ProfDM (Author), Nandini Menon, DNB (Author), Atanu Bhattacharjee, PhD (Author), Suyash Kulkarni, ProfMD (Author), Suman Kumar Ankathi, MD (Author), Abhishek Mahajan, ProfMD (Author), Nilesh Sable, ProfMD (Author), Kavita Nawale, MBA (Author), Arti Bhelekar, MSc (Author), Sadaf Mukadam, MSc (Author), Arun Chandrasekharan, DM (Author), Sudeep Das, DM (Author), Dilip Vallathol, DM (Author), Hollis D'Souza, DM (Author), Amit Kumar, DM (Author), Amit Agrawal, MD (Author), Satvik Khaddar, MD (Author), Narmadha Rathnasamy, MD (Author), Ramnath Shenoy, MD (Author), Lakhan Kashyap, MD (Author), Rahul Kumar Rai, MD (Author), George Abraham, MD (Author), Saswata Saha, MD (Author), Swaratika Majumdar, DM (Author), Naveen Karuvandan, MD (Author), Vijai Simha, DM (Author), Vasu Babu, MD (Author), Prahalad Elamarthi, MD (Author), Annu Rajpurohit, MD (Author), Kanteti Aditya Pavan Kumar, MD (Author), Anne Srikanth, MD (Author), Rahul Ravind, MD (Author), Shripad Banavali, ProfMD (Author), Kumar Prabhash, ProfDM (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
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