Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

• Asıl Yazarlar: Carmen Unzu (Yazar), Marc Friedli (Yazar), Alexis Bosman (Yazar), Marisa E. Jaconi (Yazar), Barbara E. Wildhaber (Yazar), Anne-Laure Rougemont (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2016-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Induced pluripotent stem cells (iPSC) are a most promising approach to the development of a hepatocyte transplantable mass sufficient to induce long-term correction of inherited liver metabolic diseases, thus avoiding liver transplantation. Their intrinsic self-renewal ability and potential to diffe...