Human Hepatocyte-Derived Induced Pluripotent Stem Cells: MYC Expression, Similarities to Human Germ Cell Tumors, and Safety Issues

• Główni autorzy: Carmen Unzu (Autor), Marc Friedli (Autor), Alexis Bosman (Autor), Marisa E. Jaconi (Autor), Barbara E. Wildhaber (Autor), Anne-Laure Rougemont (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2016-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Induced pluripotent stem cells (iPSC) are a most promising approach to the development of a hepatocyte transplantable mass sufficient to induce long-term correction of inherited liver metabolic diseases, thus avoiding liver transplantation. Their intrinsic self-renewal ability and potential to diffe...