Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo

• Main Authors: Kathleen R. Markan (Author), Lauren K. Boland (Author), Abdul Qaadir King-McAlpin (Author), Kristin E. Claflin (Author), Michael P. Leaman (Author), Morgan K. Kemerling (Author), Madison M. Stonewall (Author), Brad A. Amendt (Author), James A. Ankrum (Author), Matthew J. Potthoff (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: T-box 1 (TBX1) has been identified as a genetic marker of beige adipose tissue. TBX1 is a mesodermal development transcription factor essential for tissue patterning and cell fate determination. However, whether it plays a role in the process of adipose beiging or how it functions in adip...