Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

• Main Authors: Ji Hyae Lim (Author), You Jung Han (Author), Hyun Jin Kim (Author), Moon Young Kim (Author), So Yeon Park (Author), Youl-Hee Cho (Author), Hyun Mee Ryu (Author)
• Formato: Livro
• Publicado em: BMC, 2018-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background The most frequent chromosomal aneuploidy is trisomy 21 (T21) that is caused by an extra copy of chromosome 21. The imbalance of whole genome including genes and microRNAs contributes to the various phenotypes of T21. However, the integrative association between genes and microRNA...