Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile

Aim: Design and synthesis of thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors.Material and methods: A series of novel 6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine derivatives with different substituents on C-4 position was synthesized and evaluated for their anticance...

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Main Authors: Aml E.-S. Mghwary (Author), Ehab M. Gedawy (Author), Aliaa M. Kamal (Author), Suzan M. Abuel-Maaty (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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