Antinociceptive effect of cyclic phosphatidic acid and its derivative on animal models of acute and chronic pain

• Main Authors: Ogawa Tomoyo (Author), Murofushi Hiromu (Author), Hotta Harumi (Author), Gotoh Mari (Author), Nagai Jun (Author), Kakiuchi Yasutaka (Author), Ueda Hiroshi (Author), Murakami-Murofushi Kimiko (Author)
• Format: Book
• Published: SAGE Publishing, 2011-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>1. Abstract</p> <p>Background</p> <p>Cyclic phosphatidic acid (cPA) is a structural analog of lysophosphatidic acid (LPA), but possesses different biological functions, such as the inhibition of autotaxin (ATX), an LPA-synthesizing enzyme. As LPA is a signaling molec...