Toxic Responses Induced at High Doses May Affect Benchmark Doses
To derive reference points (RPs) for health-based guidance values, the benchmark dose (BMD) approach increasingly replaces the no-observed-adverse-effect level approach. In the BMD approach, the RP corresponds to the benchmark dose lower confidence bounds (BMDLs) of a mathematical dose-response mode...
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SAGE Publishing,
2020-04-01T00:00:00Z.
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