Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

• Main Authors: Alan Faraj (Author), Tom Knudsen (Author), Shraddha Desai (Author), Linda Neuman (Author), Grant E. Blouse (Author), Ulrika S. H. Simonsson (Author)
• Format: Bog
• Udgivet: Wiley, 2022-12-01T00:00:00Z.
• Fag: article
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Abstract Marzeptacog alfa (activated) (MarzAA) is an activated recombinant human FVII (rFVIIa) variant developed as subcutaneous (s.c.) administration for the treatment or prevention of bleeding episodes in patients with hemophilia A (HA) or hemophilia B (HB) with inhibitors and other rare bleeding...