The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance

• Asıl Yazarlar: Maija Toppila (Yazar), Maria Hytti (Yazar), Eveliina Korhonen (Yazar), Sofia Ranta-aho (Yazar), Niina Harju (Yazar), Markus M. Forsberg (Yazar), Kai Kaarniranta (Yazar), Aaro Jalkanen (Yazar), Anu Kauppinen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Increased oxidative stress, dysfunctional cellular clearance, and chronic inflammation are associated with age-related macular degeneration (AMD). Prolyl oligopeptidase (PREP) is a serine protease that has numerous cellular functions, including the regulation of oxidative stress, protein aggregation...