High Sugar Intake and Development of Skeletal Muscle Insulin Resistance and Inflammation in Mice: A Protective Role for PPAR-δ Agonism

• Autori principali: Elisa Benetti (Autore), Raffaella Mastrocola (Autore), Mara Rogazzo (Autore), Fausto Chiazza (Autore), Manuela Aragno (Autore), Roberto Fantozzi (Autore), Massimo Collino (Autore), Marco A. Minetto (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2013-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Peroxisome Proliferator Activated Receptor (PPAR)-δ agonists may serve for treating metabolic diseases. However, the effects of PPAR-δ agonism within the skeletal muscle, which plays a key role in whole-body glucose metabolism, remain unclear. This study aimed to investigate the signaling pathways a...