High Sugar Intake and Development of Skeletal Muscle Insulin Resistance and Inflammation in Mice: A Protective Role for PPAR-δ Agonism

• Main Authors: Elisa Benetti (Author), Raffaella Mastrocola (Author), Mara Rogazzo (Author), Fausto Chiazza (Author), Manuela Aragno (Author), Roberto Fantozzi (Author), Massimo Collino (Author), Marco A. Minetto (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peroxisome Proliferator Activated Receptor (PPAR)-δ agonists may serve for treating metabolic diseases. However, the effects of PPAR-δ agonism within the skeletal muscle, which plays a key role in whole-body glucose metabolism, remain unclear. This study aimed to investigate the signaling pathways a...